CCTV.com - CNTV English - CCTV News

2 genetic deletions linked to development of aggressive prostate cancer: study

04-10-2012 15:07 BJT

WASHINGTON, April 9 (Xinhua) -- An international research team have discovered two inherited-genetic deletions in the human genome linked to development of aggressive prostate cancer. The findings were published online Monday in the Proceedings of the National Academy of Sciences.

In the study, one genetic deletion is shown to affect the functioning of a known gene, while the other, found in a non- coding area of the genome once considered to be "junk DNA," seems to be regulating a cascade of genes.

According to the researchers led by Weill Cornell Medical College in New York, the study is potentially groundbreaking because it demonstrates that so-called copy number variations in either protein coding or non-coding areas of the human genome play a significant role in the development of cancer in general, and in aggressive prostate cancer, specifically.

The researchers speculated that the two genetic variants identified are not the only cause of aggressive prostate cancer, but "likely collaborate with other factors early in a man's life leading to development of prostate cancer."

Prostate cancer affects one in six men during their lifetime, and family history is the strongest risk factor for prostate cancer.

Editor:Wang Lingfei |Source: Xinhua

Hot Videos view more

The celebrations are still continuing as the victorious coach, Joachim Loew, has been honored for his achievement in his hometown of Freiburg.
Germany coach Loew honored in hometown of Freiburg

Chinese men´s national team continued its preparations for next year´s Asian Cup, as they managed a one-all draw against visitors Jordan during a football friendly in Harbin, the capital city of Northeast China´s Heilongjiang Province.
China held to 1-1 draw by Jordan

The defending world champs came into the contest with a perfect 6-and-oh record, but they would be in for a tough first half before opening things up in the second.
USA beat Slovenia 119-76 in quarter-finals

Hot Stories more

UK authorities believe killer of James Foley is a British national

Across the UK the hunt is on for James Foley’s killer, who authorities believe is a British national. As Richard Bestic reports from London, Prime Minister David Cameron cut short his summer break to lead his government’s response.

Israeli war jets renews Gaza strike as truce talks stalled

Three Palestinians were killed and 40 others wounded in the intensive Israeli war jets´ airstrikes on the Gaza city on Tuesday night, shortly before an end of a 24-hour ceasefire in the Gaza Strip,

Missouri police arrest dozens after violent night

As the protests in the town of Ferguson, Missouri turned violent with police facing ´heavy gunfire´ from some ´criminal elements´, cops fired tear gas, stun grenades and arrested 31 demonstrators on Monday night.

Picture in news more

More Video News

Choose TV Program